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  1. Signs of definitive chronic pancreatitis are parenchymal or intraductal calcifications, pancreatic fibrosis, exocrine and endocrine pancreatic insufficiency resulting in malabsorption and diabetes, pain, and an increased risk of pancreatic cancer. Quality of life (QOL) and life expectancy are also reduced.

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  2. 24 sty 2023 · Overall, 165 study patients died at a median age of 50.6 years. The most common cause of death was infections (16.4%), followed by cardiovascular disease (12.7%), complications of diabetes (10.9%), substance abuse (9.7%), and progressive chronic pancreatitis or failure to thrive (7.9%).

  3. Prospective investigations on long-term outcomes in chronic pancreatitis are scarce. Thus, we aimed to assess long-term survival, causes of death and impact of risk factors on survival in a cohort of surgically managed patients with chronic pancreatitis.

  4. 2 mar 2022 · The annual incidence of chronic pancreatitis in the United States ranges from 5 to 8 per 100,000 adults, and the prevalence ranges from 42 to 73 per 100,000 adults. 5 Risk factors...

  5. Chronic Pancreatitis. Acute pancreatitis can become chronic if pancreatic tissue sustains damage and scarring occurs. About 5% of patients need long-term treatment. For people with chronic pancreatitis, this can mean a lifetime of ongoing pain, nausea, and other gastrointestinal symptoms.

  6. Chronic pancreatitis – related diabetes mellitus (CP-DM) •Lifetime prevalence: up to 180% (point prevalence is ~40%) •Annual screening for DM is recommended. •Most patients will ultimately require insulin therapy, although metformin may be useful for mild hyperglycemia. Exocrine pancreatic insufficiency (EPI) •Lifetime prevalence: >70%

  7. It is an illness with variable presentations that can severely impact quality of life, while its long-term complications such as exocrine pancreatic insufficiency (EPI), diabetes mellitus, and risk of pancreatic cancer can become life threatening.

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