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  1. Signs of definitive chronic pancreatitis are parenchymal or intraductal calcifications, pancreatic fibrosis, exocrine and endocrine pancreatic insufficiency resulting in malabsorption and diabetes, pain, and an increased risk of pancreatic cancer. Quality of life (QOL) and life expectancy are also reduced.

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  2. Antecedent episodes of acute pancreatitis occur in about half of patients, so active interventions are needed to reduce the risk of disease progression. Abdominal pain is the most common symptom, and requires a tailored approach depending on the anatomic changes in the pancreas.

  3. 21 cze 2022 · Chronic pancreatitis is a progressive inflammatory disease characterized by irreversible damage to the pancreatic tissue, destroying exocrine and endocrine functions. Over time, pancreatic parenchyma is replaced by fibrotic tissue, leading to severe abdominal pain, malabsorption, and diabetes mellitus.

  4. 2 mar 2022 · Chronic pancreatitis, often associated with alcohol use, smoking, or genetic risk factors, may be complicated by pseudocysts, biliary strictures, pancreatic insufficiency, bone loss, and...

  5. The disease is manifested by abdominal pain, deterioration in quality of life, food maldigestion and malabsorption, diabetes, and an increased risk for pancreatic adenocarcinoma. This review summarizes the latest evidence on the diagnosis and management of chronic pancreatitis and its manifestations.

  6. Chronic Pancreatitis. Acute pancreatitis can become chronic if pancreatic tissue sustains damage and scarring occurs. About 5% of patients need long-term treatment. For people with chronic pancreatitis, this can mean a lifetime of ongoing pain, nausea, and other gastrointestinal symptoms.

  7. Is the Whipple procedure harmful for long-term outcome in treatment of chronic pancreatitis? 15-years follow-up comparing the outcome after pylorus-preserving pancreatoduodenectomy and Frey procedure in chronic pancreatitis.

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