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What's new? Highlights the challenge of identifying G6PD deficiency in infants. Bases follow-up testing on the difference between bilirubin level and the phototherapy threshold. No more risk zones! Raises thresholds for phototherapy and exchange transfusion. Includes gestational age and risk factors for neurotoxicity in the thresholds.
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1 cze 2007 · Severe hyperbilirubinemia – a total serum bilirubin (TSB) concentration greater than 340 µmol/L at any time during the first 28 days of life. Critical hyperbilirubinemia – a TSB concentration greater than 425 µmol/L during the first 28 days of life.
31 paź 2023 · This guideline covers diagnosing and treating jaundice, which is caused by increased levels of bilirubin in the blood, in newborn babies (neonates). It aims to help detect or prevent very high levels of bilirubin, which can be harmful if not treated.
18 sty 2021 · Hyperbilirubinemia affects approximately 60% of full-term and 80% of preterm neonates. 1 Approximately 10% of newborns are likely to develop clinically significant hyperbilirubinemia requiring close monitoring and treatment. 2 In the early period (0–6 days), neonatal hyperbilirubinemia accounted for 1309.3 deaths per 100 000 livebirths and ...
Physiological jaundice is first observed in the face when the serum bilirubin (SBR) is at least 80-120 micromol/L. There is a slow cephalocaudal progression — from face to trunk to the limbs, which are usually spared. The rate of rise of bilirubin is less than 8.5 micromol/L/h.
6 lis 2019 · Neonatal jaundice is a clinical manifestation of elevated total serum bilirubin (TSB), termed neonatal hyperbilirubinemia, which results from bilirubin that is deposited into an infant's skin. The characteristic features of neonatal jaundice include yellowish skin, sclerae, and mucous membranes.
5 sie 2022 · Use total serum bilirubin concentrations; do not subtract direct-reacting or conjugated bilirubin from the total serum bilirubin. In rare cases of severe hyperbilirubinemia in which the direct-reacting or conjugated bilirubin exceeds 50% of the TSB, consult an expert.
