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For neonates born at ≥ 35 weeks gestation, phototherapy is an option when unconjugated bilirubin is > 12 mg/dL (> 205.2 micromol/L) and may be indicated when unconjugated bilirubin is > 15 mg/dL (257 micromol/L) at 25 to 48 hours, 18 mg/dL (308 micromol/L) at 49 to 72 hours, and 20 mg/dL (342 micromol/L) at > 72 hours (see Figure: Risk of ...
What's new? Highlights the challenge of identifying G6PD deficiency in infants. Bases follow-up testing on the difference between bilirubin level and the phototherapy threshold. No more risk zones! Raises thresholds for phototherapy and exchange transfusion. Includes gestational age and risk factors for neurotoxicity in the thresholds.
Neonatal hyperbilirubinemia, characterised by the elevation of total serum bilirubin (TSB), is one of the most common clinical conditions affecting newborns, particularly preterm infants.
5 sie 2022 · Use total serum bilirubin concentrations; do not subtract direct-reacting or conjugated bilirubin from the total serum bilirubin. In rare cases of severe hyperbilirubinemia in which the direct-reacting or conjugated bilirubin exceeds 50% of the TSB, consult an expert.
11 wrz 2024 · More than 80% of newborn infants experience jaundice as a result of elevated bilirubin during the first few weeks after birth. In most cases, hyperbilirubinemia is physiologic, but persistent and extreme elevations can lead to serious long-term complications, such as kernicterus.
27 cze 2018 · Neonatal hyperbilirubinaemia is attributable to a metabolic imbalance favouring bilirubin production over hepatic-enteric bilirubin clearance. The condition affects 60% to 80% of newborn babies, and is a leading cause of hospitalisation in the first week of life. •.
1 mar 2024 · Neonatal hyperbilirubinemia, also known as jaundice, is a common condition in the neonatal period due to the adaptation of bilirubin metabolism that occurs during this time. Approximately 60 % of term infants and 80 % of preterm infants develop jaundice in their first week of life.
