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For term infants, specific indications are serum bilirubin ≥ 20 mg/dL (≥ 342 micromol/L) at 24 to 48 hours or ≥ 25 mg/dL (≥ 428 micromol/L) at > 48 hours and failure of phototherapy to result in a 1- to 2-mg/dL (17- to 34-micromol/L) decrease within 4 to 6 hours of initiation or at the first clinical signs of kernicterus regardless of ...
5 sie 2022 · Infants 7 days or older with a persistently elevated TSB within 2 mg/dL of the phototherapy threshold may have prolonged indirect hyperbilirubinemia, which can be confirmed by measuring serum direct-reacting or conjugated bilirubin (ie, a fractionated bilirubin measure) in addition to total bilirubin.
Bases follow-up testing on the difference between bilirubin level and the phototherapy threshold. No more risk zones! Raises thresholds for phototherapy and exchange transfusion. Includes gestational age and risk factors for neurotoxicity in the thresholds.
31 paź 2023 · This guideline covers diagnosing and treating jaundice, which is caused by increased levels of bilirubin in the blood, in newborn babies (neonates). It aims to help detect or prevent very high levels of bilirubin, which can be harmful if not treated.
Neonatal hyperbilirubinemia, characterised by the elevation of total serum bilirubin (TSB), is one of the most common clinical conditions affecting newborns, particularly preterm infants. Hyperbilirubinemia affects approximately 60% of full-term and 80% of preterm neonates.1 Approximately 10% of newborns are likely to develop clinically ...
4 maj 2021 · International guidelines for the management of neonates with unconjugated hyperbilirubinemia include treatment thresholds that are based on total serum bilirubin (TSB) concentrations....
24 lut 2024 · Fig. 1 Total serum bilirubin measurements and associated treatment decisions over the first 6 days of life among infants born prior to 35 weeks of gestation. Overall, 59% of patients were prescribed phototherapy in the first 24 hours of life.
