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21 lip 2020 · This article helps us understand the true relationship between time-to-antibiotics and mortality for patients with suspected sepsis and septic shock. Strich and colleagues [ 19 ] provide guidance on empiric antimicrobial therapy in an era of increasing antimicrobial resistance.
12 lut 2019 · Optimum strategies to manage the acute episode are well developed and based on evidence from high quality and large scale multi-centre clinical trials. Strategies to prevent and treat sepsis sequelae are less well developed and should be a priority for future research.
4 maj 2018 · Sepsis is a serious disease condition which harms our populations and challenges healthcare delivery. In recent years, prevention, early diagnosis and management have risen to the fore in pursuit of saving lives. Addressing sepsis requires a multidisciplinary and comprehensive approach at the global level. Sepsis is estimated to affect more ...
2 mar 2024 · The intricacy of sepsis, coupled with individual variability in immune responses influenced by health status, genetic predisposition, and infecting organisms, highlights the need for personalized therapeutic approaches in managing sepsis [30,39].
8 sty 2021 · Sepsis, a dysregulated immune response due to life-threatening organ dysfunction, caused by drug-resistant pathogens, is a major global health threat contributing to high disease burden. Clinical outcomes in sepsis depend on timely diagnosis and appropriate early therapeutic intervention.
9 wrz 2018 · To reduce the burden of sepsis, public health organizations should partner with clinical communities to create initiatives that prevent infections that can lead to sepsis and promote clinician knowledge about recommended early sepsis recognition and care.
1 kwi 2022 · Regardless of adult, maternal, or paediatric sepsis, common learning topics addressed across all studies were assessing for signs and symptoms of sepsis, investigation of sepsis diagnosis, and timely and appropriate management of sepsis.