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25 wrz 2019 · Neuroscientists have identified key molecular markers and electrophysiological characteristics of various sensory neuron subtypes, enabling a more intricate understanding of the sensory neuron function, sensory deficits, and pain.
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Neuroscientists have identified key molecular markers and...
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7 lip 2017 · The human CNS has approximately 86 billion neurons, with a roughly equal number of glial cells, and 99.9% of these neurons are located in the brain (i.e., the forebrain, brain stem, and cerebellum; Herculano-Houzel et al., 2015; Silbereis et al., 2016; Williams and Herrup, 1988).
Here, we test whether donor PSC-derived mouse and rat neurons can functionally complement genetic mouse models of (1) neural cell loss and (2) synaptic impairment, using the well-characterized and genetically tractable circuits of the olfactory system.
9 lip 2022 · Activity-dependent synaptic plasticity is a ubiquitous property of the nervous system that allows neurons to communicate and change their connections as a function of past experiences.
3 paź 2017 · The idea that plasticity mechanisms can operate throughout the lifespan suggests that many functional properties of sensory neurons can be altered, and even reversed in some cases. This is particularly relevant for neurodegenerative and neuropsychiatric conditions where plasticity mechanisms appear to be dysregulated.
20 maj 2013 · Key Points. Integration of multiple sensory cues is crucial for adaptive behaviour, but understanding its neural basis has been hampered by a divergence in the literature into two largely...
3 maj 2017 · Their breakthrough, described in a fascinating article in this issue of Neuron (Severson et al., 2017), will hopefully pave the way for a whole battery of studies that will illuminate the functional aspects of receptor morphology and location in the follicle, and likely also in other sensory organs.
