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An effective epilepsy treatment plan for dogs should reduce seizure frequency, minimize adverse drug effects, and maximize quality of life.
ly initiated at a. dose of 2 to3 mg/kg PO q12h in dogs and cats. A loading dose of12 mg/kg (range, 10 to 16 mg/kg) can be given in emergency situations.7 However, administering this dose in. fractions of 4 mg/kg q4-6h may prevent oversedation in patients. Dose adjustments are made based on therapeutic.
Adjust dosage in all species by monitoring serum levels and seizure diary. Dogs: 2–4 mg/kg, PO, bid (starting dose); up to 10 mg/kg, bid. 40–90 hr (Beagles 25–38 hr) 10–24 days. 15–45 mcg/mL (66–200 μmol/L), preferably keep values within 20–35 mcg/mL (85–150 μmol/L)
A variety of drugs can be used to stop seizures in dogs and cats. Benzodiazepines: Diazepam is the most common benzodiazepine used in dogs and cats to reduce motor activity and permit placement of an IV catheter. When used as an IV bolus (0.5–2 mg/kg), the dose may be repeated up to three times at intervals of 5–10 min.
22 lut 2016 · Preclinical studies performed on healthy dogs by the drug manufacturer described unsteady gait, salivation, vomiting, and sedation with repeated PO dosing at 300–1200 mg/kg/day (5–20 times the recommended dosage for dogs). 91 Clinical studies evaluating the use of levetiracetam as supplemental treatment in dogs with epilepsy indicated that ...
Summary. Epilepsy, defined as recurrent seizures, is caused by a heterogeneous group of conditions. The most important step in the management of seizure disorders in dogs is to establish an accurate diagnosis prior to prescribing antiepileptic drugs.
Nevertheless, one report indicated that dogs with seizures that are not well controlled with phenobarbital may respond better to primidone (eg, psychomotor seizures). The initial dosage (dogs only) is 5–15 mg/kg/day in three divided doses, increased over time to a maximum of 35 mg/kg/day.
