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29 lip 2023 · The base pairing via hydrogen bonds is the basis of RNA's secondary structure. The RNA tertiary structure is the result of RNA folding, which creates a three-dimensional shape consisting of helices and grooves.
6 paź 2022 · RNA molecules first fold into secondary structures in a process dominated by canonical Watson–Crick and wobble base pairing, before further folding into tertiary structures, driven by...
10 cze 2019 · RNAs such as microRNAs readily fold into stem-loop secondary structures, which can be recognized by proteins 6, 7, and other RNAs such as ribozymes and riboswitches can also fold into...
The sites of the tRNA interaction with the mRNA and the ribosomal peptidyl transferase, where the peptide bond synthesis takes place simultaneously, are located on different corners of the molecule. The tertiary structure of yeast tRNA Phe has been confirmed at 2 Å 39 and 1.93 Å 40 resolution.
26 cze 2021 · In particular, we highlight how different long noncoding RNAs form into distinct secondary structures that determine their modes of interactions with protein partners to realize their unique...
4 maj 2022 · The folding of an RNA is sequence-dependent. The sequence of RNA dictates its secondary and tertiary structures. The RNA structure is composed of double helices interspersed with loops of various sizes. Most helical segments in RNA are short, about 8–10 nucleotides.
RNA structural diversity, we examined RNA conservation at three structural levels: primary, secondary, and tertiary structure. Additionally, we developed an automated method for classifying RNA structures based on spatial (three-dimensional [3D]) similarity.