Search results
Recent data suggest a paraneoplastic mechanism of scleroderma pathogenesis in unique subsets of scleroderma patients. In this article, we review these data, explore potential links between cancer and scleroderma, and propose an approach to malignancy screening in scleroderma.
18 gru 2023 · Scleroderma is a condition in which skin symptoms arise from sclerosis, an autoimmune disease that sometimes affects internal organs. Look through pictures here.
Some studies suggest that diffuse scleroderma ( 5 ), an older age at scleroderma onset ( 2, 30 ), male sex ( 7, 8, 13 ), and smoking ( 25) may be factors that associate with a higher risk of cancer, yet these findings have not been consistently replicated.
9 sty 2023 · Scleroderma is characterized by progressive skin and connective tissue tightening and hardening. It may also affect subcutaneous tissue, muscles, and internal organs. There are five stages of scleroderma symptom development and progression. Stage 1: Immune system malfunction.
22 lis 2012 · Figure 1 provides the forest plot for scleroderma and all cancer risk, based on a total of 524 cancer cases. There was a significant association, with a RR of 1.75 (95% CI 1.41, 2.18) to develop all cancers in scleroderma patients compared with the general population.
This article discusses the potential mechanistic links between cancer and scleroderma, the serologic and clinical risk factors associated with increased cancer risk in patients with scleroderma, and implications for cancer screening.
ination and age-based, sex-based, and risk factor–based cancer screening tests. Recent data suggest that autoantibody and cutaneous subtype may define cancer risk, type, and timing in scleroderma.
