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8 lut 2023 · Scleroderma commonly affects people 30 to 50 years of age but is found in all ages. Also, women are typically more likely than men to receive a diagnosis of this condition.
3 lut 2022 · Systemic sclerosis (SSc), also referred to as systemic scleroderma or scleroderma, is a rare, complex immune-mediated connective tissue disease characterized by progressive skin fibrosis and other clinically heterogenous features.
15 cze 2024 · Scleroderma (sklair-oh-DUR-muh), also known as systemic sclerosis, is a group of rare diseases that involve the hardening and tightening of the skin. Scleroderma also may cause problems in the blood vessels, internal organs and digestive tract.
Scleroderma makes your body produce too much collagen, a protein that you need for healthy skin and tissue. It’s an autoimmune condition, which means your immune system attacks your body instead of protecting it. Scleroderma can cause lots of symptoms and affect tissue throughout your body.
Scleroderma is more common in women than in men. Age. The disease usually appears between the ages of 30 and 50. Race. Scleroderma can affect people of all races and ethnic groups, but the disease can affect African Americans more severely.
RESULTS. Overall, 2084 (91%) patients developed SSc prior to age 65; whereas 216 (9%) were ≥65 years. Late-age onset patients had a significantly higher proportion of anti-centromere antibodies (42% vs 27%; p=0.001) compared to younger-age onset.
The following images let you see some of the ways it can affect your skin. Hard, thickening, or tight skin. This trait is what gives scleroderma its name. Some people develop 1 or 2 patches of hard, thick skin. Others have widespread patches on their body. The hard, thick skin can feel anchored in place.