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  1. 18 gru 2023 · Table of Contents. Localized Scleroderma. Systemic Sclerosis. Other Symptoms. Scleroderma is an autoimmune condition in which the body produces too much collagen. This affects the skin by causing it to be tight and shiny and can also affect internal organs, causing significant organ dysfunction.

  2. 8 lut 2023 · Scleroderma commonly affects people 30 to 50 years of age but is found in all ages. Also, women are typically more likely than men to receive a diagnosis of this condition.

  3. Overall, 2084 (91%) patients developed SSc prior to age 65; whereas 216 (9%) were ≥65 years. Late-age onset patients had a significantly higher proportion of anti-centromere antibodies (42% vs 27%; p=0.001) compared to younger-age onset.

  4. 15 cze 2024 · Anyone can get scleroderma, but it is more common in people assigned female at birth. People typically get scleroderma between ages 30 and 50. Black people often have earlier onset and are more likely to have more skin involvement and lung disease.

  5. 3 lut 2022 · The annual incidence of SSc is estimated to be between 0.6 and 5.6 per 100,000 adults and prevalence between 7.2 and 44.3 per 100,000 adults. 1-5 Women are affected between 3.8 and 15 times more frequently than men. 1 The mean age at diagnosis is 33.5 to 59.8 years. 1 Pediatric SSc represents less than 5% of all cases.

  6. scleroderma.org › wp-content › uploadsScleroderma Facts

    • It’s estimated that there are 300,000 cases of scleroderma in the United States. • Women make up 80 percent of scleroderma cases, but men, young children and teens also get scleroderma. • Scleroderma typically strikes between the ages of 25 and 55. • In 95 percent of cases, scleroderma begins with Raynaud Phenomenon (hands and

  7. Both localized and systemic scleroderma are more common in women than in men. Both forms of the disease can affect people of any age, but systemic scleroderma is most commonly diagnosed in people between ages 20 and 50 and rarely occurs in children.

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