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  1. 18 gru 2023 · Table of Contents. Localized Scleroderma. Systemic Sclerosis. Other Symptoms. Scleroderma is an autoimmune condition in which the body produces too much collagen. This affects the skin by causing it to be tight and shiny and can also affect internal organs, causing significant organ dysfunction.

  2. 8 lut 2023 · Scleroderma commonly affects people 30 to 50 years of age but is found in all ages. Also, women are typically more likely than men to receive a diagnosis of this condition.

  3. 15 cze 2024 · Anyone can get scleroderma, but it is more common in people assigned female at birth. People typically get scleroderma between ages 30 and 50. Black people often have earlier onset and are more likely to have more skin involvement and lung disease.

  4. 4 kwi 2022 · Key points. Systemic sclerosis (SSc): autoimmune disorder of connective tissue; characterised by increased fibrosis and vascular changes; affects skin and internal organs. Types: Limited cutaneous SSc (lcSSc): skin involvement below elbows and knees, face; less internal organ involvement.

  5. 3 lut 2022 · The annual incidence of SSc is estimated to be between 0.6 and 5.6 per 100,000 adults and prevalence between 7.2 and 44.3 per 100,000 adults. 1-5 Women are affected between 3.8 and 15 times more frequently than men. 1 The mean age at diagnosis is 33.5 to 59.8 years. 1 Pediatric SSc represents less than 5% of all cases.

  6. People assigned female at birth (AFAB) are four times more likely than people assigned male at birth (AMAB) to develop scleroderma. People 30 – 50 years old — it’s rare for people younger than 30 to have scleroderma.

  7. www.nhs.uk › conditions › sclerodermaScleroderma - NHS

    In systemic sclerosis, internal organs can be affected as well as the skin. This type mostly affects women and usually develops between 30 and 50 years of age. Children are rarely affected. There are 2 types of systemic sclerosis: limited cutaneous systemic sclerosis; diffuse systemic sclerosis; Limited cutaneous systemic sclerosis:

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