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18 gru 2023 · Table of Contents. Localized Scleroderma. Systemic Sclerosis. Other Symptoms. Scleroderma is an autoimmune condition in which the body produces too much collagen. This affects the skin by causing it to be tight and shiny and can also affect internal organs, causing significant organ dysfunction.
8 lut 2023 · Scleroderma commonly affects people 30 to 50 years of age but is found in all ages. Also, women are typically more likely than men to receive a diagnosis of this condition.
Overall, 2084 (91%) patients developed SSc prior to age 65; whereas 216 (9%) were ≥65 years. Late-age onset patients had a significantly higher proportion of anti-centromere antibodies (42% vs 27%; p=0.001) compared to younger-age onset.
27 lis 2021 · Fact Sheet. Scleroderma Overview and Causes. Introduction. Scleroderma is an autoimmune disease which means that it is a condition in which the body’s immune system attacks its own tissues. The normal role of the immune system is to provide protection from outside invaders such as bacteria and viruses.
4 kwi 2022 · Systemic sclerosis (SSc): autoimmune disorder of connective tissue; characterised by increased fibrosis and vascular changes; affects skin and internal organs. Limited cutaneous SSc (lcSSc): skin involvement below elbows and knees, face; less internal organ involvement.
• It’s estimated that there are 300,000 cases of scleroderma in the United States. • Women make up 80 percent of scleroderma cases, but men, young children and teens also get scleroderma. • Scleroderma typically strikes between the ages of 25 and 55. • In 95 percent of cases, scleroderma begins with Raynaud Phenomenon (hands and
15 cze 2024 · Anyone can get scleroderma, but it is more common in people assigned female at birth. People typically get scleroderma between ages 30 and 50. Black people often have earlier onset and are more likely to have more skin involvement and lung disease.
