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Scleroderma typically strikes between the ages of 25 and 55. In 95 percent of cases, scleroderma begins with Raynaud Phenomenon (hands and feet abnormally sensitive to cold). Federal funding for scleroderma research lags behind funding for other diseases of similar prevalence.
Overall, 2084 (91%) patients developed SSc prior to age 65; whereas 216 (9%) were ≥65 years. Late-age onset patients had a significantly higher proportion of anti-centromere antibodies (42% vs 27%; p=0.001) compared to younger-age onset.
1 sty 2011 · It is important that clinicians are able to recognize features of scleroderma in the elderly and distinguish these from well-established imitators. The age of scleroderma onset can impact the course of disease and increase the risk for organ-specific complications such as pulmonary vascular disease.
It is estimated that there are over 6000 people with systemic scleroderma in Australia. Statistically, approximately three to four times more women than men develop the condition. Scleroderma is found in every age group from infants to the elderly, but its onset is most frequent between the ages of 25 to 55.
Recent studies estimate that in the US the incidence of new cases is about 20 per million adults (about 4800 new cases per year based on current US population estimates) and that the current prevalence is about 240 cases per million adults (about 60,000 total active cases).
27 kwi 2011 · Although rare in the general population, geriatricians and general practitioners should be aware of the clinical manifestations of systemic sclerosis (SSc) as it can present at an older age and may have unique patterns of organ involvement.
15 cze 2024 · People typically get scleroderma between ages 30 and 50. Black people often have earlier onset and are more likely to have more skin involvement and lung disease. Several other combined factors appear to influence the risk of having scleroderma:
