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Overall, 2084 (91%) patients developed SSc prior to age 65; whereas 216 (9%) were ≥65 years. Late-age onset patients had a significantly higher proportion of anti-centromere antibodies (42% vs 27%; p=0.001) compared to younger-age onset.
• Scleroderma typically strikes between the ages of 25 and 55. • In 95 percent of cases, scleroderma begins with Raynaud Phenomenon (hands and feet abnormally sensitive to cold).
It is estimated that there are over 6000 people with systemic scleroderma in Australia. Statistically, approximately three to four times more women than men develop the condition. Scleroderma is found in every age group from infants to the elderly, but its onset is most frequent between the ages of 25 to 55.
1 sty 2011 · In one large epidemiologic study of mortality from scleroderma in the USA, the death rate in women was the highest in the age group 65–74 years at 21.3 per million and in men aged 75–84 years at 7.5 per million.
Scleroderma may occur at any age, but the symptoms most frequently begin in mid-life (25-45). The diffuse and limited forms of scleroderma are very rare in children. The disease is about 4 times more common in women than men. There seems to be a relatively weak genetic link with scleroderma. Close order relatives of an
9 sty 2023 · The five-year survival rate (that is, patients who are still alive 5 years following diagnosis) among patients with diffuse cutaneous systemic sclerosis is about 84%. Five-year survival among patients with limited skin (cutaneous) systemic sclerosis is high — over 90%.
3 lut 2022 · The annual incidence of SSc is estimated to be between 0.6 and 5.6 per 100,000 adults and prevalence between 7.2 and 44.3 per 100,000 adults. 1-5 Women are affected between 3.8 and 15 times more frequently than men. 1 The mean age at diagnosis is 33.5 to 59.8 years. 1 Pediatric SSc represents less than 5% of all cases.
