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• Scleroderma typically strikes between the ages of 25 and 55. • In 95 percent of cases, scleroderma begins with Raynaud Phenomenon (hands and feet abnormally sensitive to cold).
It is estimated that there are over 6000 people with systemic scleroderma in Australia. Statistically, approximately three to four times more women than men develop the condition. Scleroderma is found in every age group from infants to the elderly, but its onset is most frequent between the ages of 25 to 55.
Systemic sclerosis, also known as scleroderma, is a rare and complex autoimmune connective-tissue disease. Once considered an untreatable and unpredictable condition, research advancements have improved our understanding of its disease pathogenesis and clinical phenotypes and expanded our treatment armamentarium.
RESULTS. Overall, 2084 (91%) patients developed SSc prior to age 65; whereas 216 (9%) were ≥65 years. Late-age onset patients had a significantly higher proportion of anti-centromere antibodies (42% vs 27%; p=0.001) compared to younger-age onset.
24 maj 2022 · The peak age of SSc onset is 45–60 years, and older individuals developing new-onset SSc tend to have a worse prognosis (Shah and Wigley, 2013). The disease also tends to be more severe in African Americans and Native Americans than in white Americans (Arnett et al., 1996; Otero et al., 2017; Steen et al., 2012).
25 cze 2024 · Especially the flow chart addressing the treatment of localized scleroderma subtypes with limited skin involvement (reaching to the dermis vs.) versus subtypes with severe skin and/or musculoskeletal involvement (affecting fat tissue, fascia, muscle, joints and bones, or widespread skin involvement), in adults as well as children will be very ...
3 lut 2022 · The annual incidence of SSc is estimated to be between 0.6 and 5.6 per 100,000 adults and prevalence between 7.2 and 44.3 per 100,000 adults. 1-5 Women are affected between 3.8 and 15 times more frequently than men. 1 The mean age at diagnosis is 33.5 to 59.8 years. 1 Pediatric SSc represents less than 5% of all cases.
