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Overall, 2084 (91%) patients developed SSc prior to age 65; whereas 216 (9%) were ≥65 years. Late-age onset patients had a significantly higher proportion of anti-centromere antibodies (42% vs 27%; p=0.001) compared to younger-age onset.
It is estimated that there are over 6000 people with systemic scleroderma in Australia. Statistically, approximately three to four times more women than men develop the condition. Scleroderma is found in every age group from infants to the elderly, but its onset is most frequent between the ages of 25 to 55.
1 sty 2011 · Scleroderma has a median age of onset in the fifth decade of life; however, there are many individuals who develop scleroderma later or who are aging with this disease. It is important that clinicians are able to recognize features of scleroderma in the elderly and...
9 sty 2023 · The five-year survival rate (that is, patients who are still alive 5 years following diagnosis) among patients with diffuse cutaneous systemic sclerosis is about 84%. Five-year survival among patients with limited skin (cutaneous) systemic sclerosis is high — over 90%.
Scleroderma typically strikes between the ages of 25 and 55. In 95 percent of cases, scleroderma begins with Raynaud Phenomenon (hands and feet abnormally sensitive to cold). Federal funding for scleroderma research lags behind funding for other diseases of similar prevalence.
Scleroderma may occur at any age, but the symptoms most frequently begin in mid-life (25- 45). The diffuse and limited forms of scleroderma are very rare in children.
In late 2013, the American College of Rheumatology (ACR) and the European League Against Rheumatism (EULAR) approved a new set of diagnostic criteria for systemic sclerosis (SSc), replacing the older 1980 diagnostic criteria.
