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• Scleroderma typically strikes between the ages of 25 and 55. • In 95 percent of cases, scleroderma begins with Raynaud Phenomenon (hands and feet abnormally sensitive to cold).
better understand what scleroderma is, what effects it may have, and what people with scleroderma can do to help themselves and their doctors manage the condition.
9 sty 2023 · Scleroderma is characterized by progressive skin and connective tissue tightening and hardening. It may also affect subcutaneous tissue, muscles, and internal organs. There are five stages of scleroderma symptom development and progression. Stage 1: Immune system malfunction.
Individuals with late-age onset SSc had a mean age of Raynaud onset of 65 ± 13 years, mean age of first non-Raynaud symptom of 71 ± 5 years, and 147 (68%) had the limited SSc subtype. Among individuals with SSc onset after age 75 (n=43), 34 (79%) had the limited subtype.
15 cze 2024 · People typically get scleroderma between ages 30 and 50. Black people often have earlier onset and are more likely to have more skin involvement and lung disease. Several other combined factors appear to influence the risk of having scleroderma:
Scleroderma may occur at any age, but the symptoms most frequently begin in mid-life (25- 45). The diffuse and limited forms of scleroderma are very rare in children.
25 cze 2024 · Especially the flow chart addressing the treatment of localized scleroderma subtypes with limited skin involvement (reaching to the dermis vs.) versus subtypes with severe skin and/or musculoskeletal involvement (affecting fat tissue, fascia, muscle, joints and bones, or widespread skin involvement), in adults as well as children will be very he...