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  1. 8 kwi 2022 · The primary positive, negative, and cognitive symptoms of schizophrenia have been associated with many neurotransmitters, but the subcortical dopamine dysfunction remains to be the key factor in psychotic symptoms. Presynaptic dopamine dysfunction appears to mediate psychosis in schizophrenia.

  2. 27 sie 2022 · However, schizophrenia is a syndrome including a collection of signs and symptoms with heterogeneous etiology, etiopathogenesis, and psychopathological mechanisms that are potentially implicated, with many research directions and pathways currently under investigation [18, 19, 20].

  3. 23 lut 2024 · Schizophrenia, a serious mental illness, affects 1% of the global population and is marked by hallucinations, delusions, disorganized speech, grossly disorganized behavior, and negative signs and symptoms such as reduced emotional expression, avolition, and cognitive impairment.

  4. 27 sie 2022 · However, schizophrenia is a syndrome including a collection of signs and symptoms with heterogeneous etiology, etiopathogenesis, and psychopathological mechanisms that are potentially implicated, with many research directions and pathways currently under investigation [18, 19, 20].

  5. 1 mar 2004 · In this article, we selectively review the phenomenological, genetic, psychophysiological, cognitive, imaging, and neurochemical studies that might inform the hypotheses of the pathophysiology of the schizophrenia spectrum, followed by outlines of a proposed physiological model of the schizophrenia spectrum that incorporates these findings.

  6. 18 gru 2023 · Here, we review the pathophysiology of schizophrenia, focusing on in vivo neurochemical alterations and circuits that could be targets for drug therapy, and then consider potential emerging ...

  7. Abstract. More than a century since the delineation of dementia praecox by Kraepelin, the etiology, neuropathology and pathophysiology of schizophrenia remain elusive. Despite the availability of criteria allowing reliable diagnostic identification, schizophrenia essentially remains a broad clinical syndrome defined by reported subjective ...

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