Search results
1 kwi 2023 · Abstract. Thyroid cancer incidence has been steadily rising since the 1970s and exposure to environmental pollutants, including persistent organic pollutants such as 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and other dioxins, has emerged as a potential explanation for this increase. This study aimed to summarize available human studies on the ...
1 paź 2001 · We estimated the potential influence of changes in dietary patterns in Chinese population on human health risk to 2,3,7,8-TCDD (2,3,7,8-tetrachlorodibenzo-p-dioxin) over the...
3 paź 2009 · 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) has a long half-life of 5–10 years in human beings as a result of its high lipophilicity, and little or no metabolism. We monitored TCDD, its form, distribution, and elimination in Victor Yushchenko after he presented with severe poisoning.
5 cze 2024 · See EPA’s Recommended Toxicity Equivalence Factors (TEFs) for Human Health Risk Assessments of 2,3,7,8- Tetrachlorodibenzo-p-dioxin and Dioxin-Like Compounds. A TEF for a DLC is a measure of the compound’s toxicity relative to TCDD, which is assigned a TEF of 1.
This document describes the U.S. Environmental Protection Agency‘s (EPA‘s) updated approach for evaluating the human health risks from exposures to environmental media containing dioxin-like compounds (DLCs). 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and DLCs are structurally and toxicologically related halogenated aromatic hydrocarbons.
2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) is a halogenated aromatic hydrocarbon (HAH) and widespread environmental pollutant (Poland and Knutson, 1982). TCDD is lipophilic and has a slow rate of metabolism and excretion; thus, it readily concentrates in the food chain (Safe et al., 1991).
TCDD levels in adults aged 60 or older (1.34 to 3.54 pg/g of lipid) were about twice the levels seen in adults aged 40 to 59 (0.781 to 1.17 pg/g). Among adolescents and younger adults, the proportion of results be-low the limit of detection (0.78 pg/g) was too high to allow means to be calculated.
