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11 wrz 2022 · Increased mortality may relate to development of pulmonary fibrosis, sarcoid-associated pulmonary hypertension and effects of treatment modalities . The aim of this paper is to review the published literature on LOS and discuss the challenges in diagnosing and treating older patients.
Treatment is directed at alleviating organ dysfunction, preventing irreversible scarring, and improving quality of life. Herein, we review the indications for treatment, pharmacotherapy, treatment duration, side effects, adjunct non-pharmacologic therapies, and outcomes for patients.
29 lis 2022 · How to Treat Pulmonary Sarcoidosis Induction and Maintenance Phases of Treatment. Most experts agree that short courses (e.g. a few weeks) of high-dose corticosteroids are less useful than a longer course of lower dose treatment (total of > 6 months) for long-term remission [12, 41, 42••].
Except for facial nerve palsy, which may benefit from only a few weeks of therapy, long-term treatment is the rule, and most patients also receive second- and third-line therapy. MTX is traditionally the first second-line choice, with a response rate of about 60%, as seen in pulmonary sarcoidosis .
Sarcoidosis is the commonest interstitial lung disease (ILD), differing from most other ILDs in that many patients remain asymptomatic or improve spontaneously. Careful baseline assessment of disease distribution and severity is thus central to initial management.
1 lip 2016 · Learning Objectives: On completion of this article, you should be able to (1) recognize the most common clinical presentations of pulmonary sarcoidosis, (2) perform the initial diagnostic evaluation for suspected pulmonary sarcoidosis, and (3) identify the most common causes of sarcoidlike granulomatous inflammation.
16 gru 2021 · Glucocorticoid-sparing alternatives are available. The presented treatment guidelines aim to provide guidance to physicians treating the very heterogenous sarcoidosis manifestations.
