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24 paź 2023 · At diagnosis, FVC < 70% and DLCO < 60% portend clinically significant pulmonary sarcoidosis pathology, which warrants treatment [15,64]. During follow-up, development of symptoms or an objective loss of pulmonary function reflects the progression of the disease.
22 mar 2018 · However, pulmonary function testing may show normal results even when anatomic changes documented by imaging studies are severe [14]. In one study [13], only 14.6% of consecutive newly diagnosed sarcoid patients had restriction or mixed restriction and obstruction at presentation.
The literature on pulmonary function testing in sarcoidosis is critically reviewed. The results indicate that pulmonary function tests are not a reliable means for detecting the presence of parenchymal sarcoidosis, nor do they provide an accurate estimate of the extent of parenchymal disease.
6 cze 2021 · Among the results of lung function tests, forced vital capacity (FVC) is an important parameter for monitoring disease (and response to treatment) in pulmonary sarcoidosis; the diffusing capacity of the lung for carbon monoxide (DLco) and forced expiratory volume in the first second (FEV1) are also important . A Delphi panel agreed that changes ...
Oral glucocorticoids with or without another immunosuppressive agent are the first-line therapy for symptomatic patients with abnormal pulmonary function test results and lung infiltrates. Patients with sarcoidosis and precapillary pulmonary hypertension should be treated with therapies such as phosphodiesterase inhibitors and prostacyclin ...
24 paź 2023 · At diagnosis, FVC < 70% and DLCO < 60% portend clinically significant pulmonary sarcoidosis pathology, which warrants treatment [15, 64]. During follow-up, development of symptoms or an objective loss of pulmonary function reflects the progression of the disease.
PFT data of all patients with sarcoidosis was reviewed. PFT findings were categorize in three groups; Obstructive, restrictive and obstructive-restrictive. RESULTS: Of 142 patients; 100 (70%) were females and 42 (30%) were males with median age of 45 years (range, 18-81).
