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13 wrz 2023 · Sarcoidosis may progress to pulmonary fibrosis in 5% of patients with significantly increased mortality. Histopathology shows fibrosis in a lymphangitic pattern surrounding the granulomas. Th1 to Th2 shift in environment along with angiogenesis is implicated in exuberant fibrosis.
- Sarcoidosis-associated pulmonary fibrosis: joining the dots
Sarcoidosis is a multisystem granulomatous disorder of...
- Pulmonary fibrosis in sarcoidosis. Clinical features and outcomes
There are several radiographic patterns of pulmonary...
- A Comprehensive Review of Sarcoidosis Treatment for Pulmonologists
Sarcoidosis is a systemic inflammatory granulomatous disease...
- An expert overview of pulmonary fibrosis in sarcoidosis
Areas covered: This article will focus on the pathogenesis,...
- Immune mechanisms in fibrotic pulmonary sarcoidosis - PMC
In this review, we provide a comprehensive examination of...
- Pulmonary fibrosis in sarcoidosis - PubMed
Sarcoidosis may progress to pulmonary fibrosis in 5% of...
- Sarcoidosis-associated pulmonary fibrosis: joining the dots
Sarcoidosis is a multisystem granulomatous disorder of unknown aetiology. A minority of patients with sarcoidosis develop sarcoidosis-associated pulmonary fibrosis (SAPF), which may become progressive. Genetic profiles differ between patients with progressive and self-limiting disease.
There are several radiographic patterns of pulmonary fibrosis in sarcoidosis; bronchial distortion is common, and other patterns, including honeycombing, are variably observed. The development of pulmonary fibrosis is associated with significant morbidity and can be fatal.
Sarcoidosis is a systemic inflammatory granulomatous disease mainly affecting the lungs and thoracic lymph nodes. In a previous article in this journal, we reviewed emerging aspects of diagnosis and monitoring of the disease. This narrative paper aims to review and update sarcoidosis management.
3 mar 2023 · Areas covered: This article will focus on the pathogenesis, natural history of disease, diagnosis, and potential treatment options of pulmonary fibrosis in sarcoidosis. In the expert opinion section, we will discuss the prognosis and management of patients with significant disease.
12 gru 2022 · In this review, we provide a comprehensive examination of the relevant immune findings in fibrotic and/or progressive pulmonary sarcoidosis and propose a unifying mechanism for the pathobiology of fibrosis in sarcoidosis.
13 wrz 2023 · Sarcoidosis may progress to pulmonary fibrosis in 5% of patients with significantly increased mortality. Histopathology shows fibrosis in a lymphangitic pattern surrounding the granulomas. Th1 to Th2 shift in environment along with angiogenesis is implicated in exuberant fibrosis.
