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This article discusses the pathophysiology of sarcoidosis and its medical and nursing management. A case presentation highlights some long-term concerns with this chronic disease.
The purpose of this clinical practice guideline is to make recommendations that address uncertainties that are commonly confronted by clinicians relating to the diagnosis and detection of sarcoidosis.
8 wrz 2021 · Treatment guidelines for sarcoidosis are evolving, and health care providers are advised to consider a personalized approach based on individual variations in disease manifestations (Tables S1...
We have assembled these into a concise quick-reference format article for those looking for a cohesive approach to the diagnosis and management of sarcoidosis, including when it doesn't respond to initial therapy.
Abstract. Sarcoidosis is a systemic disease of unknown etiology defined by the presence of noncaseating granulomatous inflammation that can cause organ damage and diminished quality of life. Treatment is indicated to protect organ function and decrease symptomatic burden.
29 lis 2022 · Sarcoidosis is an immune-mediated disease characterised by the presence of non-necrotizing granuloma and varying degrees of lymphocytic inflammation. In a nutshell, activated CD4 T cells with Th1 and Th17/Th17.1 bias are thought to be key drivers of granuloma formation and persistence [1, 2].
The diagnosis of sarcoidosis is not standardized but is based on the following three major criteria: a compatible clinical presentation (Table 1), the finding of nonnecrotizing granulomatous inflammation in one or more tissue samples, and the exclusion of alternative causes of granulomatous disease (Table 2).
