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30 sty 2019 · Sarcoidosis is a disease characterized by the growth of tiny collections of inflammatory cells (granulomas) in any part of your body — most commonly the lungs and lymph nodes. But it can also affect the eyes, skin, heart and other organs.
21 lut 2019 · The focus of this review is current knowledge about the epidemiology, clinical manifestations, diagnosis, and treatment of both pulmonary sarcoidosis and extrapulmonary sarcoidosis. Although intrathoracic involvement is the hallmark of the disease, present in over 90% of patients, sarcoidosis can affect virtually any organ.
2 sie 2019 · Although intrathoracic involvement is the hallmark of the disease, present in over 90% of patients, sarcoidosis can affect virtually any organ. Clinical presentations of sarcoidosis are diverse, ranging from asymptomatic, incidental findings to organ failure.
Different combinations of exposures and host defects likely determine the multiple phenotypes seen in sarcoidosis. This review summarizes the recent discov-eries regarding the pathogenesis of sarcoidosis, most common clinical presentations, diagnosis, and indications for treatment of pulmonary sarcoidosis.
Sites of Manifestation of Sarcoidosis. Open table in a new tab. Sarcoidosis may be diagnosed because of involvement of the eyes with uveitis, iritis, conjunctivitis, or perhaps dry eyes due to involvement of the lacrimal glands. Twenty-five percent of Mayo patients have such involvement.
The three major manifestations of cardiac sarcoidosis are: conduction abnormalities, ventricular arrhythmias, and congestive heart failure. Granulomatous infiltration of the myocardium is responsible for arrhythmias and cardiomyopathy [ 9 ].
Most common clinical manifestations of sarcoidosis are non-specific generalized symptoms like fever, fatigue, myalgias, arthritis which is also seen in various autoimmune disease that need to be differentiated from sarcoidosis. It may manifest acutely as Lofgren syndrome (a triad of erythema nodosum, bilateral hilar lymphadenopathy, and arthritis).
