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Approach to diagnosis of neurosarcoidosis. Patients with suspected neurosarcoidosis require a careful assessment of the systemic manifestations and neurologic evaluation. As sarcoidosis is a multiorgan disease, a diagnosis of neurosarcoidosis does not rest merely on neurologic features.
- Sarcoidosis and the Nervous System
Abstract. Purpose of review: This article provides an...
- Sarcoidosis and the Nervous System
Neurosarcoidosis is an uncommon but potentially serious manifestation of sarcoidosis. While the cranial nerves are most frequently affected, neurosarcoidosis can involve other nervous system tissues including the meninges, brain parenchyma (especially the hypothalamic region), spinal cord, peripheral nerve, and muscle.
Abstract. Purpose of review: This article provides an overview and update on the neurologic manifestations of sarcoidosis. Recent findings: The 2018 Neurosarcoidosis Consortium diagnostic criteria emphasize that biopsy is key for diagnosis and determines the level of diagnostic certainty.
Sarcoidosis affects the nervous system in 5% to 15% of all patients (neurosarcoidosis). Neurosarcoidosis is therefore uncommon (only 20 cases per million people) but can be severe. Nonetheless, provided with expert care, the disease is usually straightforward to treat.
12 paź 2022 · Sarcoidosis is a systemic granulomatous disease that can affect multiple organ systems including the lungs, liver, heart, eyes, lymphatics, and the central and peripheral nervous system. Neurosarcoidosis refers to sarcoidosis involving a variety of neural tissue types including the meninges, brain parenchyma, spinal cord and peripheral nerves.
15 lis 2016 · The most commonly reported feature of neurosarcoidosis was cranial neuropathy in 55%, with the facial and optic nerve most commonly affected, followed by headache in 32%. Pleiocytosis and elevated CSF protein were found in 58 and 63%. MRI of the brain showed abnormalities in 70%.
Neurosarcoidosis can manifest in a myriad of ways including: cranial neuropathy, aseptic meningitis, mass lesions, encephalopathy, vasculopathy, seizures, hypothalamic-pituitary disorders, hydrocephalus, myelopathy, peripheral neuropathy, and myopathy.
