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12 sie 2024 · 44 of bivalent Salmonella Typhi/Paratyphi A vaccines against enteric fever for use in low- and 45 middle-income countries (LM Is). It is designed for use by key stakeholders to outline
2 cze 2023 · Typhoid conjugate vaccines are efficacious against Salmonella Typhi. Globally, most Salmonella disease in humans is caused by non-Typhi Salmonella serovars. Nontyphoidal Salmonella and paratyphoid require combination Salmonella vaccines. A quadrivalent Salmonella vaccine could prevent a large majority of Salmonella disease.
With other new vaccines under investigation, including live-attenuated, protein-based and GMMA vaccines, now is an exciting time for the Salmonella vaccine field. Keywords: vaccines, Salmonella, nontyphoidal, typhoid, enteric, global health, glycoconjugate, GMMA. Protection Against more than Diarrhea
EFSA evaluates the risks for public health from infected animals and provides recommendations and advice on control and reduction measures. For example, EFSA has provided advice on reduction targets in poultry and poultry meat and the use of vaccines and antimicrobials for the control of Salmonella.
Salmonella Vaccines. Though primarily enteric pathogens, Salmonellae are responsible for a considerable yet under-appreciated global burden of invasive disease. In South and South-East Asia, this manifests as enteric fever caused by serovars Typhi and Paratyphi A. In sub-Saharan Africa, a similar disease burden results …
In this review we focus on (1) recent advances in live attenuated Salmonella vaccine development, (2) improvements in expression of foreign antigens in carrier vaccines and (3) adaptation of attenuated strains as sources of purified antigens and vesicles that can be used for subunit and conjugate vaccines or together with attenuated vaccine ...
We aimed to systematically review the prevalence of complications and case-fatality ratio (CFR) of non-typhoidal salmonella invasive disease to provide contemporary global estimates and inform the development of vaccine and non-vaccine interventions. Lancet Infect Dis 2022; 22: 692–705. Published Online. January 31, 2022 https://doi.org/10.1016/