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The well-recognized clinical association between HIV infection and iNTS disease, particularly among individuals with CD4 counts below 200 cells/µl, 42 also appears to provide clear support for the importance of cell mediated immunity in defense against Salmonella.
- Advances in the development of Salmonella-based vaccine ... - PubMed
In this review we focus on (1) recent advances in live...
- Advances in the development of Salmonella-based vaccine ... - PubMed
In this review we focus on (1) recent advances in live attenuated Salmonella vaccine development, (2) improvements in expression of foreign antigens in carrier vaccines and (3) adaptation of attenuated strains as sources of purified antigens and vesicles that can be used for subunit and conjugate vaccines or together with attenuated vaccine ...
Salmonella Vaccines. Though primarily enteric pathogens, Salmonellae are responsible for a considerable yet under-appreciated global burden of invasive disease. In South and South-East Asia, this manifests as enteric fever caused by serovars Typhi and Paratyphi A.
There are currently three vaccines licensed for use in humans, all targeting typhoidal Salmonella: the live attenuated oral vaccine S. Typhi Ty21a, Vi capsule polysaccharide vaccine, and Vi polysaccharide conjugated with tetanus toxoid ( 11 – 14 ).
7 maj 2014 · Vaccines against invasive Salmonella disease. Current status and future directions. Calman A MacLennan. , Laura B Martin. & Francesca Micoli. Pages 1478-1493 | Received 13 Feb 2014, Accepted 29 Apr 2014, Published online: 07 May 2014. Cite this article. https://doi.org/10.4161/hv.29054. Article contents. Related research. Full Article.
1 lis 2002 · The use of Salmonella vaccines as candidate typhoid fever vaccines and as carriers of heterologous antigens will be reviewed. In addition, problems associated with their development, and solutions to these problems, which have been devised, are discussed.
30 wrz 2024 · Effective vaccines against Salmonella-related diseases must stimulate both humoral immunity to combat extracellular bacteria and cellular immunity to eliminate intracellular pathogens. This multifaceted strategy is vital for effectively addressing Salmonella infections.
