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1. www.cancer.gov › about-cancer › causes-preventionArtificial Sweeteners and Cancer - NCI - National Cancer...

   www.cancer.gov › about-cancer › causes-prevention

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   Concerns about artificial sweeteners and cancer initially arose when early studies linked the combination of cyclamate plus saccharin (and, to a lesser extent, cyclamate alone) with the development of bladder cancer in laboratory animals, particularly male rats.

   • Obesity and Cancer

     Obesity is a disease in which a person has an unhealthy...

   • Gastrointestinal Tract

     Gastrointestinal Tract - Artificial Sweeteners and Cancer -...

   • Calories

     Calories - Artificial Sweeteners and Cancer - NCI - National...

   • Diabetes

     Any of several diseases in which the kidneys make a large...

   • Animal Studies

     Animal Studies - Artificial Sweeteners and Cancer - NCI -...

   • Lymphoma

     Lymphoma - Artificial Sweeteners and Cancer - NCI - National...

   • World Health Organization

     A part of the United Nations that deals with major health...

   • Kidney Cancer

     It forms in the lining of the tiny tubes in the kidney that...

2. www.akc.org › expert-advice › nutritionArtificial Sweeteners: Which Ones Are Safe for Dogs? - American...

   www.akc.org › expert-advice › nutrition

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   21 gru 2023 · Saccharin is safe for dogs, but eating it can cause gastrointestinal issues. Long-term effects on pets have not yet been examined. Sucralose (Yellow Packet)

3. pmc.ncbi.nlm.nih.gov › articles › PMC10146554Impact of Long-Term Cyclamate and Saccharin Consumption on...

   pmc.ncbi.nlm.nih.gov › articles › PMC10146554

   According to Zeynep and Sifa (2014), sweeteners may cause a variety of health problems, including cancer. Their arguments are based on studies dating to the 1970s, which linked saccharin to bladder cancer in laboratory rats.

4. www.sciencedirect.com › science › articleNon-sugar sweeteners and cancer: Toxicological and...

   www.sciencedirect.com › science › article

   1 mar 2023 · Initial genotoxicity studies on sodium saccharin that produced some positive results for in vitro chromosomal aberrations (CA) and sister chromatide exchanges (SCE) tests are now considered non-specific effects likely resulting from the very high doses used (SCF, 1995).

5. www.sciencedirect.com › science › articleArtificial sweeteners—do they bear a carcinogenic risk?

   www.sciencedirect.com › science › article

   1 paź 2004 · In the USA, since 1981, saccharin-containing products have had to be labeled with a warning that saccharin can cause cancer in laboratory animals. However, the National Institute for Environmental Health Sciences, which issues a biannual report, removed saccharin as a potential cancer-causing agent, because it could be shown that the cancer ...

6. academic.oup.com › jnci › articleIs Saccharin Safe? Animal Testing Revisited - Oxford Academic

   academic.oup.com › jnci › article

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   7 sty 1998 · Results from standard long-term rodent carcinogenicity tests indicate that sodium saccharin is a weak carcinogen and tumor promoter in the male rat bladder, particularly when it is administered in a two-stage, initiation-promotion protocol with specific bladder genotoxic carcinogens such as N-butyl-N-(4-hydroxybutyl)nitrosamine and N-[4-(5 ...

7. pmc.ncbi.nlm.nih.gov › articles › PMC9506029Can Artificial Sweeteners Increase the Risk of Cancer Incidence...

   pmc.ncbi.nlm.nih.gov › articles › PMC9506029

   High-intensity sweeteners approved by the Food and Drug Administration (FDA) include six artificial sweeteners (saccharin, aspartame, acesulfame potassium (Ace-K), sucralose, neotame and aspartame) and two natural sweeteners (stevia (steviol glycosides) and Monk fruit) [8].