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1. www.op.gg › champions › vayneVayne Build - Highest Win Rate Builds, Runes, and Items - OP.GG

   www.op.gg › champions › vayne

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   Vayne Build with the highest win rate. Runes, items, and skill build in patch 14.20. Vayne build recommendations and guides.

   • Vayne Rune Guide - Best Runes for Every Role by Win Rate - OP.GG

     Vayne rune builds. Vayne runes for each position by win rate...

2. www.mobafire.com › league-of-legends › championVayne Build Guides, Runes, Items, and Abilities - Patch 14.20

   www.mobafire.com › league-of-legends › champion

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   Below you can find the best items and runes to build for Vayne, as determined by calculations of thousands of Plat+ League of Legends games. If you are already familiar with how to play Vayne this is a great resource to quickly get a good rune selection for Patch 14.20.

3. mobalytics.gg › lol › championsVayne Build Guide - Runes, Items & More - Patch 14.20 -...

   mobalytics.gg › lol › champions

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   Get the best Vayne builds, based on analysis of 10000+ matches in all regions and ranks. Climb in patch 14.20 with Vayne builds provided by Mobalytics!

4. u.gg › lol › championsVayne Build with Highest Winrate - LoL Runes, Items, and Skill...

   u.gg › lol › champions

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   Vayne with U.GG's best data for every build. The highest win rate Vayne build, from rune set to skill order to item path, for ADC. LoL Patch 14.20

5. www.probuilds.net › lol › championsVayne Build for ADC with Highest Winrate, Guides, Runes, Items

   www.probuilds.net › lol › champions

   Vayne with Blitz's best data for every build. The highest win rate Vayne build, from rune set to skill order to item path, for ADC. LoL Patch 14.20

6. www.metasrc.com › lol › buildVayne Build 14.20 - Runes, Items, Counters - LoL - METAsrc

   www.metasrc.com › lol › build

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   For runes, the strongest choice is Precision (Primary) with Lethal Tempo (Keystone), and Resolve (Secondary). The optimal Summoner Spells for this build are Flash and Barrier. Starting items should include Doran's Blade, Health Potion, and Stealth Ward. Vayne's Best ADC matchups include Corki, Singed, and Zeri.

7. www.op.gg › champions › vayneVayne Rune Guide - Best Runes for Every Role by Win Rate - OP.GG

   www.op.gg › champions › vayne

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   Vayne rune builds. Vayne runes for each position by win rate and pick rate. LoL 14.20