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Structure. Rubella virus is a spherical, 40- to 80-nm, positive-sense, single-stranded RNA virus with spike-like, hemagglutinin-containing surface projections. An electron-dense 30 to 35 nm core is surrounded by a lipoprotein envelope.
26 kwi 2021 · This review focuses on the life cycle of RUBV with emphasis on recent findings on the structures of the virus particle and its component proteins and on the mechanisms of virus entry, fusion, assembly, and budding.
28 sie 2019 · Rubella or German measles is an infection caused by rubella virus (RV). Infection of children and adults is usually characterized by a mild exanthematous febrile illness. However, RV is a major cause of birth defects and fetal death following infection in pregnant women.
26 kwi 2021 · This review concentrates on recent work on RUBV, focusing on the virion, its structural components, and its entry, fusion, and assembly mechanisms. Important features of RUBV are compared with those of viruses from other families.
2 kwi 2022 · Rubella viruses are classified into two clades and 13 genotypes that differ by about 8–10% in the nucleotide sequence of 3 proximal third of the genome, which codes for the structural proteins. Genotyping requires sequencing of 739 nucleotides in the E1 protein coding region.
2 cze 2017 · Here we report a helical structure of rubella virions using cryo-electron tomography. Sub-tomogram averaging of the surface spikes established the relative positions of the viral glycoproteins, which differed from the earlier icosahedral models of the virus.
Rubella virus contains three major structural polypeptides designated El, E2, and C with molecular weights of 62,000, 47,000-54,000 (a complex), and 38,000, respectively, as de-termined by sodium dodecyl sulfate-polyacrylamide gel electrophoresis under reduced conditions. Limited-digest peptide maps confirm that each of these polypeptides is dis-
