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Chronic kidney disease (CKD) is cumulative worldwide and an increasing public health issue. Aside from the widely known protein restriction and medical therapy, less evident is the renal protection of nutrition supplements in CKD patients.
Retroperitoneal fibrosis is a rare cause of renal dysfunction, typically presenting with obstructive uropathy (sometimes with extra-renal manifestations). Given its insidious and subtle presentation, reaching the diagnosis can be challenging.
26 paź 2016 · Retroperitoneal fibrosis (RPF) is a chronic inflammatory disease characterized by progressive entrapment of ureters and vessels in the retroperitoneum leading to ureteral obstruction and renal failure.
1 maj 2024 · Renal plasma flow – the perfusion of the glomerulus is an important determinant of GFR, as the blood flow provides the required hydrostatic pressure for ultrafiltration. The RPF is determined by the pressure gradient through the renal vasculature divided by the total renal vascular resistance.
30 gru 2020 · RPF is a long-term condition with a relapsing nature causing patients to experience a variety of chronic symptoms associated with acute flares including flank pain, constipation, constitutional symptoms, such as night sweats, nausea and reduced appetite.
10 gru 2020 · INTRODUCTION. The ability of glomerular filtration rate (GFR) to increase in response to a challenge such as an oral protein or intravenous amino acid load (14, 21, 60, 76, 86) or unilateral nephrectomy (87, 91) has long been of interest to renal physiologists and nephrologists and has led to the concept of renal functional reserve (RFR).
The fibrosis of RPF can compress the ureters and block the flow of urine from the kidneys (see How the disease works below). If this occurs, urine flow can be restored using a stent. The stent, a slender tube, is inserted in the ureter holding it open for urine to flow freely.
