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  1. www.ncbi.nlm.nih.gov › pmc › articlesRole of metformin in the management of polycystic ovary syndrome

    Several effects have been reported as related to metformin in PCOS patients including restoring ovulation, reducing weight, reducing circulating androgen levels, reducing the risk of miscarriage and reducing the risk of gestational diabetes mellitus (GDM).

    • PubMed

      The classification of diabetes mellitus and the tests used...

  2. www.uptodate.com › contents › metformin-for-treatment-of-the-polycystic-ovary-syndromeMetformin for treatment of the polycystic ovary syndrome

    1 gru 2022 · OVERVIEW. Interest in the use of metformin, an insulin-lowering drug, in PCOS increased when it was appreciated that insulin resistance played an important role in the pathophysiology of the disorder. However, we no longer recommend the use of metformin as a first-line therapy for any indication in women with PCOS.

  3. www.bmj.com › content › 327/7421/951Metformin in polycystic ovary syndrome: systematic review and...

    23 paź 2003 · Results Meta-analysis showed that metformin is effective in achieving ovulation in women with polycystic ovary syndrome, with odds ratios of 3.88 (95% confidence interval 2.25 to 6.69) for metformin compared with placebo and 4.41 (2.37 to 8.22) for metformin and clomifene compared with clomifene alone.

  4. www.ncbi.nlm.nih.gov › pmc › articlesThe use of metformin in women with polycystic ovary syndrome: an...

    14 lut 2022 · Insulin resistance (IR) plays an important role in the pathophysiology of PCOS; therefore, its treatment may benefit women with the syndrome. The main drug used for IR management is metformin (MT). We aim to review the literature on the use of metformin in women with PCOS.

  5. www.ncbi.nlm.nih.gov › pmc › articlesMetformin use in women with polycystic ovary syndrome

    15 kwi 2014 · Metformin is an effective ovulation induction agent for non-obese women with PCOS and offers some advantages over other first line treatments for anovulatory infertility such as clomiphene. For clomiphene-resistant women, metformin alone or in combination with clomiphene is an effective next step.

  6. www.fertstert.org › article › S0015-0282(20)31938-5METFORMIN SHOULD BE RECOMMENDED FOR MORE PATIENTS WITH PCOS BASED...

    Among these guidelines are updated recommendations for the use of metformin in patients with PCOS. These recommendations advise that patients with PCOS and BMI≥25, impaired glucose tolerance, and/or adolescents age <18 should take metformin to prevent metabolic sequelae of PCOS (1).

  7. link.springer.com › content › pdfMetformin in women with PCOS, CONS - Springer

    Metformin has a potential role for insulin resistance in polycystic ovary syndrome(PCOS) and has demonstrated efficacy in diabetes.