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  1. Several effects have been reported as related to metformin in PCOS patients including restoring ovulation, reducing weight, reducing circulating androgen levels, reducing the risk of miscarriage and reducing the risk of gestational diabetes mellitus (GDM).

    • PubMed

      The classification of diabetes mellitus and the tests used...

  2. 11 sty 2024 · In clinical practice, metformin is a recommended first step for managing PCOS in overweight or obese patients, particularly when oral contraceptives are not suitable or insulin resistance is ...

  3. 23 paź 2003 · Results Meta-analysis showed that metformin is effective in achieving ovulation in women with polycystic ovary syndrome, with odds ratios of 3.88 (95% confidence interval 2.25 to 6.69) for metformin compared with placebo and 4.41 (2.37 to 8.22) for metformin and clomifene compared with clomifene alone.

  4. 1 lut 2008 · Metformin treatment improved insulin sensitivity and decreased serum apelin, LH and testosterone levels in both groups; lean PCOS patients showed better response to metformin treatment. View...

  5. Among these guidelines are updated recommendations for the use of metformin in patients with PCOS. These recommendations advise that patients with PCOS and BMI≥25, impaired glucose tolerance, and/or adolescents age <18 should take metformin to prevent metabolic sequelae of PCOS (1).

  6. 11 kwi 2021 · Three CPGs recommended combining LSTs with pharmacological treatments such as metformin to optimize weight loss after 6 months (13,19,20), and 3 recommended bariatric surgery in obese women with PCOS if LST alone failed to achieve sufficient weight loss (14,15,20).

  7. Metformin is best taken during or immediately after a meal to reduce stomach pain, nausea and diarrhoea. The dose may vary depending on what your doctor prescribes, but taking metformin tablets at the same time each day will have the best effect. It will also help you remember when to take your tablets.