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During mitosis, a eukaryotic cell undergoes a carefully coordinated nuclear division that results in the formation of two genetically identical daughter cells. Mitosis itself consists of...
- Mitotic spindle assembly in animal cells: a fine balancing act
The mitotic spindle has a crucial role in ensuring the...
- The role of 3D genome organization in development and cell ...
The 3D organization of chromatin modulates biological...
- Mitotic spindle assembly in animal cells: a fine balancing act
8 lut 2017 · The mitotic spindle has a crucial role in ensuring the accurate segregation of chromosomes into the two daughter cells during cell division, which is paramount for maintaining genome...
20 cze 2019 · How replicated sister DNA molecules are folded during G2, and how the transition from cohesin to condensin-mediated chromosome organisation as cells enter mitosis changes this folding, are also important unresolved questions.
The complex task of packaging DNA is accomplished by specialized proteins that bind to and fold the DNA, generating a series of coils and loops that provide increasingly higher levels of organization, preventing the DNA from becoming an unmanageable tangle.
31 paź 2020 · In order to perform the proper cell division, a cell needs to duplicate its DNA content, which is termed DNA replication. The cell cycle process itself involves several phases, such as G1-, S-, G2- and M-phases. A cell can also be in a rest phase, termed G0-phase, in which no cell doubling occurs.
13 cze 2019 · The 3D organization of chromatin modulates biological processes such as transcription, DNA replication, cell division and meiosis, which are crucial for cell differentiation and animal...
1 cze 2020 · Every cell in our body contains several meters of DNA that must be folded in exactly the right way. This important process turns out to be entirely dependent on the binding of two proteins within the cell: cohesin (green) and CTCF (purple).
