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1 sty 2023 · Rete ridges (RRs) are distinct undulating microstructures at the junction of the dermis and epidermis in the skin of humans and certain animals. This structure is essential for enhancing the mechanical characteristics of skin and preserving homeostasis.
1 sty 2023 · The findings reveal that this microstructure provides a stem cell niche that regulates the pathways and promotes the expression of proteins related to epidermal stem cells. This work advances the functional properties of tissue engineered skin and holds promise for improving the therapeutic efficacy of artificial skin grafts for the skin wounds.
1 sty 2023 · Rete ridges (RRs) are distinct undulating microstructures at the junction of the dermis and epidermis in the skin of humans and certain animals. This structure is essential for enhancing the mechanical characteristics of skin and preserving homeostasis.
Rete ridges surround the dermal papillae, which can be seen as small extensions protruding from the papillary dermis within the epidermis. These two structures are perfectly embedded; the alternation of a rete ridge with a dermal papilla creates a characteristic repetitive and wave-shaped pattern.
During human skin development, specific interactions between epidermal and dermal cell lineages give rise to fully functional skin that contains specialized appendages, including hair follicles, sweat glands, and rete ridges.
1 sty 2016 · The epidermis penetrates down into the dermis through the rete ridges, while the dermis projects upward into the epidermis by the dermal papillae that occur between these rete ridges (Fig. 1.1). The epidermis is separated from the dermis by the basement membrane, which will be explained in this chapter.
25 lis 2015 · Focusing on the rete ridges and complementary dermal papillae in human skin, we review the identity and organisation of abundant dermal cells types and present evidence for interactions between the dermal microenvironment and the interfollicular keratinocytes.
