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7 lip 2018 · If the response is minimal, a different anticholinergic agent should be selected. Combinations of agents rarely provide significant clinical improvement and only increase the potential side effects. Commonly reported adverse side effects include confusion, drowsiness, and urinary retention.
23 maj 2023 · The respiratory therapies for ALS summarized in this review, including mechanical insufflation-exsufflation, lung volume replacement, noninvasive ventilation, and respiratory strength training can be applied in conjunction with pharmacological approaches, to help stabilize respiratory function in ALS.
Amyotrophic lateral sclerosis (ALS) is a fatal and incurable disease requiring a multidisciplinary treatment approach and a collaborative therapeutic effort. A combination of both upper and lower motor neuron degeneration ultimately leads to respiratory failure, similar to other dementia-type neurodegenerative diseases.
6 sty 2012 · Respiratory complications are a common cause of morbidity and mortality in amyotrophic lateral sclerosis (ALS). Treatment of respiratory insufficiency with noninvasive ventilation (NIV) improves ALS patients' quality of life and survival.
Although clinical presentations can vary, there is no cure for ALS, and the disease is universally terminal, with most patients dying of respiratory complications. Patients die, on average, within 3 to 5 years of diagnosis, unless they choose to undergo tracheostomy, in which case, they may live, on average, 2 additional years.
Amyotrophic lateral sclerosis (ALS) is a rapidly progressive neurodegenerative disorder affecting upper and lower motor neurons, with death resulting mainly from respiratory failure three to five years after symptom onset.
Respiratory training or physical exercise did not significantly affect the ALSFRS-R score and % FVC of patients with ALS. At 12 months after intervention, the ALSFRS-R score in the physical exercise group was higher than that in the usual care group. Further clinical trials are warranted to develop …
