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7 lip 2018 · Although chronic respiratory failure can be supported rather effectively with NIV, acute episodes are much more difficult to manage. Generation of adequate cough is vital for mucus clearance during these acute episodes and is often significantly limited in patients with ALS.
23 mar 2018 · Death often results from respiratory failure within 3–5 years. Monitoring respiratory status is therefore critical to ALS management, as respiratory/pulmonary function tests (PFTs) are used to make decisions including when to initiate noninvasive ventilation.
1 sty 2023 · In contrast to the scarcity of data in the early stages, as the disease progresses, it is increasingly enriched by a rich set of symptoms and positive respiratory tests until respiratory failure occurs, which represents the main cause of death in ALS.
Abstract. Amyotrophic lateral sclerosis is a progressive neuromuscular disease characterized by both lower motor neuron and upper motor neuron dysfunction. Although clinical presentations can vary, there is no cure for ALS, and the disease is universally terminal, with most patients dying of respiratory complications.
15 mar 2022 · Our study of early affected patients supports the use of a set of volitional and non-volitional respiratory tests to assess disease progression, rather than any single test. We found MVV a potentially useful marker of pulmonary function in ALS.
19 sty 2023 · A comprehensive, multidisciplinary approach to ALS respiratory care may minimize hospitalizations for acute respiratory failure, reduce need for emergent tracheostomy, improve patient-reported outcome measures, and facilitate developing clinical research initiatives.
In some people with ALS, difficulty breathing is their first symptom of the disease. This resource guide will teach you the basics of how the lungs function, the changes that will occur, how to be proactive in maintaining lung health, and how to prepare for the decisions that will need to be made when the lungs need maximal assistance.
