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7 lip 2018 · This article discusses noninvasive ventilation in the management of respiratory muscle weakness, mechanical insufflation/exsufflation devices for airway clearance, and treatment of aspiration, including timing of placement of a percutaneous endoscopic gastrostomy tube, as well as secretion management.
28 kwi 2022 · Consequently, the most common cause of death for people with ALS is respiratory failure. To prevent this, some people in the end stages of the disease could permanently need ventilatory support. 2 Other patients may choose to undergo a tracheostomy to facilitate full-time respirator use. 2.
Up to 95% of patients with ALS in the United States choose not to undergo tracheostomy; management of respiratory failure is therefore aimed at both prolonging survival as well as improving quality of life.
15 kwi 2015 · ALS leads to death in 15 to 20 months after diagnosis in 50 % of patients [2••], generally due to respiratory failure. An older age and bulbar involvement at onset are the main negative prognostic factors. Ten percent survives more than 10 years.
19 sty 2023 · A comprehensive, multidisciplinary approach to ALS respiratory care may minimize hospitalizations for acute respiratory failure, reduce need for emergent tracheostomy, improve patient-reported outcome measures, and facilitate developing clinical research initiatives.
ALS with respiratory onset has some common clinical features: male predominance, frequent camptocormia or dropped head, frequent widespread fasciculations, limb mobility fairly well preserved and significant weight loss in the early stages.
Amyotrophic lateral sclerosis (ALS) is an incurable disease whereby patients most commonly die of respiratory complications. It is important for pulmonary physicians to be aware of this and understand management options, including noninvasive and invasive ventilation and assisted cough techniques.
