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7 lip 2018 · Respiratory system dysfunction is the terminal event for most patients with ALS. Despite variable presentations, a vast majority of patients eventually experience difficulty with speech, airway clearance, and aspiration as bulbar muscle coordination declines. 6 In ALS
15 kwi 2015 · ALS leads to death in 15 to 20 months after diagnosis in 50 % of patients [2••], generally due to respiratory failure. An older age and bulbar involvement at onset are the main negative prognostic factors. Ten percent survives more than 10 years.
Amyotrophic Lateral Sclerosis Neurology Neuromuscular Diseases Critical Care Medicine Respiratory Failure and Ventilation. This Viewpoint describes the dearth of noninvasive ventilation for patients with amyotrophic lateral sclerosis in the US and proposes methods to increase.
The goal of this review was to serve as an overview of respiratory considerations in the management of ALS. This article discusses noninvasive ventilation in the management of respiratory muscle weakness, mechanical insufflation/exsufflation devices for airway clearance, and treatment of aspiration, including timing of placement of a ...
19 sty 2023 · A comprehensive, multidisciplinary approach to ALS respiratory care may minimize hospitalizations for acute respiratory failure, reduce need for emergent tracheostomy, improve patient-reported outcome measures, and facilitate developing clinical research initiatives.
ALS with respiratory onset has some common clinical features: male predominance, frequent camptocormia or dropped head, frequent widespread fasciculations, limb mobility fairly well preserved and significant weight loss in the early stages.
23 maj 2023 · Respiratory upper and lower motor neuron degeneration in ALS leads to weakness and atrophy of the inspiratory and expiratory muscles, as well as muscles of the upper airway. Isolated or combined dysfunction of these motor neuron pools leads to hypoventilation, dystussia, and dysphagia in patients. Open in viewer.
