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  1. 7 lip 2018 · Respiratory system dysfunction is the terminal event for most patients with ALS. Despite variable presentations, a vast majority of patients eventually experience difficulty with speech, airway clearance, and aspiration as bulbar muscle coordination declines. 6 In ALS

  2. 28 kwi 2022 · Consequently, the most common cause of death for people with ALS is respiratory failure. To prevent this, some people in the end stages of the disease could permanently need ventilatory support. 2 Other patients may choose to undergo a tracheostomy to facilitate full-time respirator use. 2

  3. 19 sty 2023 · A comprehensive, multidisciplinary approach to ALS respiratory care may minimize hospitalizations for acute respiratory failure, reduce need for emergent tracheostomy, improve patient-reported outcome measures, and facilitate developing clinical research initiatives.

  4. Amyotrophic Lateral Sclerosis Neurology Neuromuscular Diseases Critical Care Medicine Respiratory Failure and Ventilation. This Viewpoint describes the dearth of noninvasive ventilation for patients with amyotrophic lateral sclerosis in the US and proposes methods to increase.

  5. Up to 95% of patients with ALS in the United States choose not to undergo tracheostomy; management of respiratory failure is therefore aimed at both prolonging survival as well as improving quality of life.

  6. 15 kwi 2015 · ALS leads to death in 15 to 20 months after diagnosis in 50 % of patients [2••], generally due to respiratory failure. An older age and bulbar involvement at onset are the main negative prognostic factors. Ten percent survives more than 10 years.

  7. 16 kwi 2024 · This study aimed to systematically review the literature on non-invasive interventions for controlling breathlessness in ALS patients and their effects on (1) overall symptom control and (2) overall QOL.