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7 lip 2018 · Although chronic respiratory failure can be supported rather effectively with NIV, acute episodes are much more difficult to manage. Generation of adequate cough is vital for mucus clearance during these acute episodes and is often significantly limited in patients with ALS.
28 kwi 2022 · Consequently, the most common cause of death for people with ALS is respiratory failure. To prevent this, some people in the end stages of the disease could permanently need ventilatory support. 2 Other patients may choose to undergo a tracheostomy to facilitate full-time respirator use. 2
Amyotrophic lateral sclerosis is a progressive neuromuscular disease characterized by both lower motor neuron and upper motor neuron dysfunction. Although clinical presentations can vary, there is no cure for ALS, and the disease is universally terminal, with most patients dying of respiratory compl ….
19 sty 2023 · A comprehensive, multidisciplinary approach to ALS respiratory care may minimize hospitalizations for acute respiratory failure, reduce need for emergent tracheostomy, improve patient-reported outcome measures, and facilitate developing clinical research initiatives.
The majority of ALS patients are either on MIE or should be at some point in the disease process. In general, their lungs are free from pathology and O2 (as loud as one expects from an O2 concentrator behind a patient's head) is not indicated and the same for nebulizer function.
Amyotrophic lateral sclerosis (ALS) is a relentlessly progressive neurodegenerative disease that affects the brain and spinal cord motor neurons leading to progressive muscle weakness, irreversible disability, respiratory failure and death within a time range of a few months to more than 10 years [ 1 ].
15 kwi 2015 · ALS leads to death in 15 to 20 months after diagnosis in 50 % of patients [2••], generally due to respiratory failure. An older age and bulbar involvement at onset are the main negative prognostic factors. Ten percent survives more than 10 years.
