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  1. The goal of this review was to serve as an overview of respiratory considerations in the management of ALS. This article discusses noninvasive ventilation in the management of respiratory muscle weakness, mechanical insufflation/exsufflation devices for airway clearance, and treatment of aspiration, including timing of placement of a ...

  2. 3 lis 2016 · Respiratory failure, infections and aspiration pneumonia, are the main causes of morbidity and mortality in Amyotrophic Lateral Sclerosis (ALS). In a population-based cohort, we assessed (a) hospital utilization and (b) impact of hospitalization for respiratory failure on survival.

  3. 19 sty 2023 · A comprehensive, multidisciplinary approach to ALS respiratory care may minimize hospitalizations for acute respiratory failure, reduce need for emergent tracheostomy, improve patient-reported outcome measures, and facilitate developing clinical research initiatives.

  4. 22 lut 2022 · Respiratory dysfunction is a common cause of morbidity and mortality in many neuromuscular disorders, but particularly important in motor neuron diseases (MND), such as amyotrophic lateral sclerosis (ALS) or spinal muscular atrophy (SMA).

  5. 6 sty 2012 · Respiratory complications are a common cause of morbidity and mortality in amyotrophic lateral sclerosis (ALS). Treatment of respiratory insufficiency with noninvasive ventilation (NIV) improves ALS patients' quality of life and survival.

  6. ALS causes multiple problems that impact the respiratory system. Fig. 1 provides an overview of the most relevant complications. ALS causes diffuse muscle weakness that ultimately leads to functional quadriplegia and anarthria.

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