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  1. The hypocretin-producing cell destruction contributes to most of the symptoms of narcolepsy, including EDS with sleep onset REM periods (SOREMPs), and other symptoms reflecting exaggerated REM sleep pressure such as cataplexy, sleep paralysis, hypnagogic/hypnopompic hallucinations, and REM sleep behavior disorder (RBD), all disclosing an ...

  2. 14 sty 2023 · REM sleep is when most dreaming happens. Typically, people enter REM sleep 60 to 90 minutes after falling asleep. But people with narcolepsy often move more quickly to REM sleep. They tend to enter REM sleep within 15 minutes of falling asleep. REM sleep also can happen at any time of the day.

  3. 31 lip 2024 · Narcolepsy is a chronic condition characterised by a disruption of the sleep-wake cycle and rapid eye movement (REM) sleep intrusion. The classic tetrad of narcolepsy, includes excessive daytime sleepiness, cataplexy, sleep paralysis, and hypnagogic/hypnopompic hallucinations.

  4. 19 lip 2024 · Treating narcolepsy. Although there is no cure for narcolepsy, some of the symptoms can be treated with medicines and lifestyle changes. Medications. ModafinilThe initial line of treatment is usually a central nervous system stimulant such as modafinil.

  5. 1 paź 2024 · Medications used to treat narcolepsy (and REM-related symptoms of narcolepsy) include stimulants/wake-promoting agents, pitolisant, oxybates, and antidepressants; hypocretin agonists are a potential new class of therapeutics.

  6. 12 cze 2023 · Narcolepsy is a disorder of rapid onset rapid eye movement (REM) sleep characterized by excessive daytime sleepiness (EDS), frequent uncontrollable sleep attacks as well as sleep fragmentation and can be associated with cataplexy, sleep paralysis, and hypnagogic hallucinations.

  7. 2 maj 2024 · Key Takeaways. Narcolepsy affects the brain’s ability to regulate sleep-wake cycles and causes persistent daytime sleepiness. Additional symptoms include disrupted sleep, sleep paralysis, and sleep-related hallucinations. Treatment for narcolepsy focuses on managing symptoms and reducing accident risk.