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31 sty 2019 · Characteristic sleep-EEG changes in patients with depression include disinhibition of rapid eye movement (REM) sleep, changes of sleep continuity, and impaired non-REM sleep. Most antidepressants suppress REM sleep both in healthy volunteers and depressed patients.
- A Narrative Review on REM Sleep Deprivation: A Promising Non ...
Wu et al. developed a REM sleep fragmentation-based...
- Sleep, insomnia, and depression - PubMed
The so-called Cholinergic REM Induction Test revealed that...
- A Narrative Review on REM Sleep Deprivation: A Promising Non ...
9 maj 2019 · The introduction of polysomnography into psychiatric research confirmed a disturbance of sleep continuity in patients with depression, revealing not only a decrease in Slow Wave Sleep, but...
5 sie 2024 · The relationship between mental disorders and sleep remains unclear. Two new studies show that the lateral habenula, a brain region associated with value-guided behavior, controls REM sleep and promotes emotional stability but also contributes to REM sleep disinhibition in depression.
10 lut 2023 · Wu et al. developed a REM sleep fragmentation-based regression model that could predict the risk of endogenous depression with an 83.7% prediction accuracy, thus promoting REM as a viable index for estimating depression risk and a biomarker for treatment response .
29 maj 2024 · In this review, we aim to highlight the role of rapid eye movement (REM) sleep instability, defined as fragmented or unstable REM sleep (see below), for pathophysiological considerations concerning chronic insomnia (insomnia disorder, ID) and its link to mental illness, especially depression and anxiety disorders.
The so-called Cholinergic REM Induction Test revealed that REM sleep abnormalities can be mimicked by administration of cholinomimetic agents. Another important research avenue is the study of chrono-medical timing of sleep deprivation and light exposure for their positive effects on mood in depression.
7 lut 2019 · According to studies with polysomnography, SSRIs, SNRIs and activating TCAs increase rapid eye movement sleep (REM sleep, REMS) latency, suppress REM sleep and impair sleep continuity.
