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19 kwi 2023 · Regenerating hair cells through gene therapy approach. Studies like Chen’s show the promise of gene therapy for treating incurable conditions like hearing loss. Last year, this research project was selected out of hundreds as one of the Disruptive Dozen gene and cell therapy technologies most likely to have a significant impact on health care ...
17 lut 2021 · Cell transplantation and HF regeneration. Cell-based transplantation without biomaterials is a minimally invasive approach to in vivo HF regeneration. Current cell transplantation mainly...
Cruz et al. used transgenic fish (myo6b: NLS-Eos) to track hair cell regeneration after damage, and found that supporting cells regenerate hair cells via three regionally and temporally distinct mechanisms—those in the anterior-posterior pole undergo slow cell division prior to regenerating hair cells, whereas those in the dorso-ventral pole ...
Because mammalian hair cells do not regenerate, the repair of hair cell damage is important for continued auditory function throughout life. Here we discuss how several key hair cell structures can be damaged, and what is known about how they are repaired.
4 cze 2022 · Hair regeneration depends on the activity of multiple distinct populations of hair follicle stem cells (HFSCs). Hair growth and cycling may also be modulated by fibroblasts in the dermal papilla and dermal sheath, dermal adipocytes, immune cells, lymphatic and blood vessels, and nerves.
26 mar 2024 · Sensory cells in the cochlea, known as hair cells, are essential for auditory perception. Hair cells are compact cylindrical cells that convert mechanical stimuli of their apical hair bundle into the release of synaptic vesicles at afferent synapses with the dendrites of auditory neurons.
1 sty 2024 · In this review, we investigated the mechanisms underlying HF development and regeneration. For this, we studied the structure, development, cycle, and cellular function of HFs. In addition, we analyzed the symptoms, types, and causes of hair loss as well as its current conventional treatments.
