Search results
Cruz et al. used transgenic fish (myo6b: NLS-Eos) to track hair cell regeneration after damage, and found that supporting cells regenerate hair cells via three regionally and temporally distinct mechanisms—those in the anterior-posterior pole undergo slow cell division prior to regenerating hair cells, whereas those in the dorso-ventral pole ...
Because mammalian hair cells do not regenerate, the repair of hair cell damage is important for continued auditory function throughout life. Here we discuss how several key hair cell structures can be damaged, and what is known about how they are repaired.
24 maj 2022 · These studies motivated efforts to identify therapeutic interventions to regenerate hair cells as a treatment for hearing loss, with a focus on targeting supporting cells to form new sensory hair cells.
1 sty 2024 · In this review, we investigated the mechanisms underlying HF development and regeneration. For this, we studied the structure, development, cycle, and cellular function of HFs. In addition, we analyzed the symptoms, types, and causes of hair loss as well as its current conventional treatments.
17 lut 2021 · Regeneration. Regenerative medicine. Abstract. The hair follicle (HF) is a highly conserved sensory organ associated with the immune response against pathogens, thermoregulation, sebum...
19 kwi 2023 · Regenerating hair cells through gene therapy approach. Studies like Chen’s show the promise of gene therapy for treating incurable conditions like hearing loss. Last year, this research project was selected out of hundreds as one of the Disruptive Dozen gene and cell therapy technologies most likely to have a significant impact on health care ...
13 kwi 2019 · Given that mammalian hair cells do not regenerate, the repair of hair cell damage is important for continued auditory function throughout life. Here, we discuss how several key hair cell structures can be damaged, and what is known about how they are repaired.
