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It has been shown that use of pyrimethamine is safe in rabbits when used at the right dosage. The anti-protozoal drug will directly attack the parasite, where it will both block the metabolism of folic acid in the parasite and increase the activity of trimethoprim-sulfa against the parasite.
12 maj 2024 · hello - i am looking for experiences made with "daraprim" (pyrimethamine) in order to treat E.C. when Panacur doesn't help. i read that EC can get resistent to panacur due to several treatments in the past.
Toxoplasmosis is an uncommon cause of torticollis or other neurologic signs in the pet rabbit. Transmission is primarily by ingestion of infected cat feces. Serologic tests are available for antemortem diagnosis, and affected rabbits may be treated with pyrimethamine combined with a sulfa drug as for other companion animals. 15
Sulfonamides are used in combination with pyrimethamine to treat protozoal diseases such as leishmaniasis and toxoplasmosis. ( See also page Regulatory Considerations and Drug Withdrawal and Milk Discard Times .)
15 maj 2018 · Current consensus is that perioperative multimodal analgesia is the best practice. However, it is not widely used in rabbits. In rabbits, analgesia protocols and dosages reported in the literature are often poorly researched and do not result in complete pain amelioration with the return of normal.
14 paź 2024 · Use glucocorticosteroids with care in rabbits as they act as strong immunodepressants. Wear gloves when applying cream. Topical corticosteroids should not be used on animals with ulcerative keratitis.
Pyrimethamine was not teratogenic in rabbits at dose levels up to 100 mg/kg bodyweight/day administered on days 6 to 18 of pregnancy. Pyrimethamine markedly reduced early stage cell division in rabbit embryos but implantation and foetal development were normal.
