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  1. 31 sie 2000 · Here we report the complete sequence of P. aeruginosa strain PAO1. At 6.3 million base pairs, this is the largest bacterial genome sequenced, and the sequence provides insights into the basis...

  2. 13 paź 2022 · Sequencing of PAO1 revealed that P. aeruginosa has more regulatory genes than other sequenced bacteria genomes. The bacterium also has higher expression of transcriptional regulators in the LysR, AraC, ECF-σ, and two-component regulator families (Stover et al., 2000).

  3. 4 lip 2024 · Trajectories were inferred as the sequence of mutations in pathoadaptive genes since the emergence of the clone ancestor as implied by the PAO1-rooted tree stratified by CF and non-CF infection types.

  4. 22 cze 2021 · The wild-type parent of PAO1 was lost, and PAO1 carries a regulatory mutation introduced for positive genetic selection that affects antibiotic resistance, virulence, quorum sensing, and other traits.

  5. 19 paź 2021 · P. aeruginosa strain PAO1 from log-phase culture (~ 0.1 OD 600) was seeded into wounds and then harvested for RNA-Seq after 2 and 6 h (H2 and H6, colonization), 24 h (H24, acute infection), 5...

  6. 6 sty 2020 · Results. Here we report the genome sequence of P. aeruginosa PAO1161 laboratory strain, a leu -, Rif R, restriction-modification defective PAO1 derivative, described as the host of IncP-8 plasmid FP2, conferring the resistance to mercury.

  7. 1 mar 2017 · In the current study we analysed the mexT gene sequence in four PAO1 sublines and six DNA polymerase-deficient transposon mutants of MPAO1 from the two-allele transposon mutant library.